What are the most common symptoms? Celiac disease can affect many different organs and systems in the body, resulting in a wide variety of symptoms that vary from person to person. The most common symptoms are: Diarrhea or constipation Weight loss or weight gain Fatigue Vomiting In children, failure to grow Other symptoms such as anemia, osteoporosis, and vitamin or mineral deficiencies may also occur. Celiac disease is suspected in some individuals because they have a non-intestinal complaint that may be associated with celiac disease, such as a skin condition called dermatitis herpetiformis (itchy skin rash made up of raised red patches which may cluster), mouth ulcers, diabetes, osteoporosis, infertility, thyroid disease, allergies, food intolerance, or a neurological condition. In addition many persons who are gluten Intolerant can suffer from the same issues as Celiac.